21th I have mirgated to cassandra 1.1.2 but see no improvement 

cat /var/log/cassandra/Earth1.log | grep "GC for"
INFO [ScheduledTasks:1] 2012-05-22 17:42:48,445 GCInspector.java (line 123) GC 
for ParNew: 345 ms for 1 collections, 82451888 used; max is 8464105472
INFO [ScheduledTasks:1] 2012-05-23 02:47:13,911 GCInspector.java (line 123) GC 
for ParNew: 312 ms for 1 collections, 110617416 used; max is 8464105472
INFO [ScheduledTasks:1] 2012-05-23 11:57:54,317 GCInspector.java (line 123) GC 
for ParNew: 298 ms for 1 collections, 98161920 used; max is 8464105472
INFO [ScheduledTasks:1] 2012-07-02 08:52:37,019 GCInspector.java (line 123) GC 
for ParNew: 196886 ms for 1 collections, 2310058496 used; max is 8464105472
INFO [ScheduledTasks:1] 2012-07-16 17:41:25,940 GCInspector.java (line 123) GC 
for ParNew: 200146 ms for 1 collections, 2345987088 used; max is 8464105472
=== Migrated from 1.0.0 to 1.1.2
INFO [ScheduledTasks:1] 2012-07-21 09:05:08,280 GCInspector.java (line 122) GC 
for ParNew: 282 ms for 1 collections, 466406864 used; max is 8464105472
INFO [ScheduledTasks:1] 2012-07-21 12:38:43,132 GCInspector.java (line 122) GC 
for ParNew: 233 ms for 1 collections, 405269504 used; max is 8464105472
INFO [ScheduledTasks:1] 2012-07-22 02:29:09,596 GCInspector.java (line 122) GC 
for ParNew: 253 ms for 1 collections, 389700768 used; max is 8464105472
INFO [ScheduledTasks:1] 2012-07-22 17:45:46,357 GCInspector.java (line 122) GC 
for ParNew: 57391 ms for 1 collections, 400083984 used; max is 8464105472

Memory and yaml memory-related settings are default 
I do not do deletes
I have 2 CF's and no secondary indexes

LiveRatio's:
 INFO [pool-1-thread-1] 2012-06-09 02:36:07,759 Memtable.java (line 177) 
CFS(Keyspace='Keyspace1', ColumnFamily='PSS') liveRatio is 1.0 (just-counted 
was 1.0).  calculation took 85ms for 6236 columns
 INFO [MemoryMeter:1] 2012-07-21 09:04:47,614 Memtable.java (line 213) 
CFS(Keyspace='Keyspace1', ColumnFamily='Standard1') liveRatio is 1.0 
(just-counted was 1.0).  calculation took 8ms for 1 columns
 INFO [MemoryMeter:1] 2012-07-21 09:04:51,012 Memtable.java (line 213) 
CFS(Keyspace='Keyspace1', ColumnFamily='PSS') liveRatio is 1.0 (just-counted 
was 1.0).  calculation took 99ms for 1094 columns
 INFO [MemoryMeter:1] 2012-07-21 09:04:51,331 Memtable.java (line 213) 
CFS(Keyspace='Keyspace1', ColumnFamily='Standard1') liveRatio is 1.0 
(just-counted was 1.0).  calculation took 80ms for 242 columns
 INFO [MemoryMeter:1] 2012-07-21 09:04:51,856 Memtable.java (line 213) 
CFS(Keyspace='Keyspace1', ColumnFamily='PSS') liveRatio is 1.0 (just-counted 
was 1.0).  calculation took 505ms for 2678 columns
 INFO [MemoryMeter:1] 2012-07-21 09:04:52,881 Memtable.java (line 213) 
CFS(Keyspace='Keyspace1', ColumnFamily='PSS') liveRatio is 1.0 (just-counted 
was 1.0).  calculation took 776ms for 5236 columns
 INFO [MemoryMeter:1] 2012-07-21 09:04:52,945 Memtable.java (line 213) 
CFS(Keyspace='Keyspace1', ColumnFamily='Standard1') liveRatio is 1.0 
(just-counted was 1.0).  calculation took 64ms for 389 columns
 INFO [MemoryMeter:1] 2012-07-21 09:04:55,162 Memtable.java (line 213) 
CFS(Keyspace='Keyspace1', ColumnFamily='PSS') liveRatio is 1.0 (just-counted 
was 1.0).  calculation took 1378ms for 8948 columns
 INFO [MemoryMeter:1] 2012-07-21 09:04:55,304 Memtable.java (line 213) 
CFS(Keyspace='Keyspace1', ColumnFamily='Standard1') liveRatio is 1.0 
(just-counted was 1.0).  calculation took 140ms for 1082 columns
 INFO [MemoryMeter:1] 2012-07-21 09:05:08,439 Memtable.java (line 213) 
CFS(Keyspace='Keyspace1', ColumnFamily='Standard1') liveRatio is 
2.5763038186160894 (just-counted was 2.5763038186160894).  calculation took 
8796ms for 102193 columns

18.07.2012, 07:51, "aaron morton" <aa...@thelastpickle.com>:
> Assuming all the memory and yaml settings default that does not sound 
> right. The first thought would be the memory meter not counting correctly...
> Do you do a lot of deletes ?
> Do you have a lot of CF's and/or secondary indexes ?
> Can you see log lines about the "liveRatio" for your cf's ?
> I would upgrade to 1.0.10 before getting too carried away though.
> Cheers
>
> -----------------
> Aaron Morton
> Freelance Developer
> @aaronmorton
> http://www.thelastpickle.com
>
> On 17/07/2012, at 8:14 PM, Nikolay Kоvshov wrote:
>
>> This is a cluster of 2 nodes, each having 8G of operating memory, 
>> replicationfactor=2
>> Write/read pressure is quite low and almost never exceeds 10/second
>>
>> From time to time (2-3 times in a month) I see GC activity in logs and for 
>> this time cassandra stops responding to requests which results in a timeout 
>> in upper-layer application. Total time of unavailability can be over 5 
>> minues (like in the following case)
>>
>> What can I do with that? Wiil it become much worse when my cluster grows up?
>>
>> INFO [GossipTasks:1] 2012-07-16 13:10:50,055 Gossiper.java (line 736) 
>> InetAddress /10.220.50.9 is now dead.
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,056 GCInspector.java (line 123) 
>> GC for ParNew: 391383 ms for 1 collections, 2025808488 used; max is 
>> 8464105472
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,067 StatusLogger.java (line 50) 
>> Pool Name                    Active   Pending   Blocked
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,071 StatusLogger.java (line 65) 
>> ReadStage                         0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,071 StatusLogger.java (line 65) 
>> RequestResponseStage              0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,072 StatusLogger.java (line 65) 
>> ReadRepairStage                   0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,072 StatusLogger.java (line 65) 
>> MutationStage                     0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,073 StatusLogger.java (line 65) 
>> ReplicateOnWriteStage             0         0         0
>>  INFO [GossipStage:1] 2012-07-16 13:10:50,074 Gossiper.java (line 722) 
>> InetAddress /10.220.50.9 is now UP
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,075 StatusLogger.java (line 65) 
>> GossipStage                       1        59         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,075 StatusLogger.java (line 65) 
>> AntiEntropyStage                  0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,076 StatusLogger.java (line 65) 
>> MigrationStage                    0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,076 StatusLogger.java (line 65) 
>> StreamStage                       0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,077 StatusLogger.java (line 65) 
>> MemtablePostFlusher               0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,077 StatusLogger.java (line 65) 
>> FlushWriter                       0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,077 StatusLogger.java (line 65) 
>> MiscStage                         0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,078 StatusLogger.java (line 65) 
>> InternalResponseStage             0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,078 StatusLogger.java (line 65) 
>> HintedHandoff                     0         0         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,079 StatusLogger.java (line 69) 
>> CompactionManager               n/a         0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,079 StatusLogger.java (line 81) 
>> MessagingService                n/a       0,0
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,080 StatusLogger.java (line 85) 
>> ColumnFamily                Memtable ops,data  Row cache size/cap  Key cache 
>> size/cap
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,080 StatusLogger.java (line 88) 
>> Keyspace1.PSS                 36712,343842617                 0/0       
>> 97995/1000000
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,085 StatusLogger.java (line 88) 
>> Keyspace1.Standard1          128679,162567721                 0/0           
>> 0/1000000
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,085 StatusLogger.java (line 88) 
>> system.NodeIdInfo                         0,0                 0/0            
>>      0/1
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,086 StatusLogger.java (line 88) 
>> system.IndexInfo                          0,0                 0/0            
>>      0/1
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,086 StatusLogger.java (line 88) 
>> system.LocationInfo                       0,0                 0/0            
>>      1/2
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,086 StatusLogger.java (line 88) 
>> system.Migrations                         0,0                 0/0            
>>      3/3
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,087 StatusLogger.java (line 88) 
>> system.HintsColumnFamily                1,528                 0/0            
>>      0/1
>>  INFO [ScheduledTasks:1] 2012-07-16 13:10:50,087 StatusLogger.java (line 88) 
>> system.Schema                             0,0                 0/0            
>>      2/3
>> -------- Завершение пересылаемого сообщения --------

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