I understand that every environment is different and it always 'depends' :) But recommending settings and techniques based on an existing real production environment (like the user's suggestion to run nodetool repair as a regular cron job) is always a better starting point for a new Cassandra evaluator than having to start from scratch.
Ryan, do you have any 'seed' settings that you guys use for nodes at Twitter? Are there any resources/write-ups beyond the two I've listed already that address some of these 'gotchas'? If those two links are in fact the ideal starting point, that's fine - but it appears that this may not be the case however based on the aforementioned user as well as the other who helped him who saw similar warning signs. I'm hoping for someone to dispel these reports based on what people actually do in production today. Any info/settings/recommendations based on real production environments would be appreciated! Thanks again, Les