same issue here (Problem loading X.509 certificate -65) after upgrading from 20.04 to 22.04 but system starts up normal and can be operated normal. Read here (https://askubuntu.com/questions/1218700/integrity- problem-loading-x-509-certificate-65) that it's related to Acer BIOS (mine is an Acer Laptop; don't know if OP too)
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