I had the same issue and I disabling the default for Wayland also resolved it for me.
(I had to uncomment the line #WaylandEnable=false in /etc/gdm3/custom.conf.) Initially after updating from 17.04 to 17.10 I had no troubles. For me this mouse issue appeared some time after (not right away) using ppa:ubuntu-x-swat/updates for the latest Mesa releases. By the way, also mouse hovering over an element that would usually focus on hovering over it did not work for me in a Wayland session. -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1747568 Title: Mouse clicks ignored in Wayland To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/gnome-shell/+bug/1747568/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs