Public bug reported:

Fresh install Ubuntu 16.04 Xenial Xerus, server distro, apt update ; apt
dist-upgrade -y ; apt install ubuntu-desktop -y ; shutdown -r now.

Firefox would not open, stating "profile cannot be loaded, may be
missing or inaccessible". Checked ownership of ~/.mozilla ; all files
were owned user:user and fine.  Did a chown -R user.user ~/.mozilla
anyway, problem persisted.  Then did ls -lah ~ | grep cache, saw .cache
owned root.root.

Did chown -R ~/.cache user.user, then Firefox opened fine.

ProblemType: Bug
DistroRelease: Ubuntu 16.04
Package: firefox 47.0+build3-0ubuntu0.16.04.1
ProcVersionSignature: Ubuntu 4.4.0-31.50-generic 4.4.13
Uname: Linux 4.4.0-31-generic x86_64
AddonCompatCheckDisabled: False
ApportVersion: 2.20.1-0ubuntu2.1
Architecture: amd64
AudioDevicesInUse:
 USER        PID ACCESS COMMAND
 /dev/snd/controlC0:  jrs        4503 F.... pulseaudio
BuildID: 20160606113944
Channel: Unavailable
CurrentDesktop: Unity
Date: Fri Jul 22 18:17:46 2016
EcryptfsInUse: Yes
Extensions: extensions.sqlite corrupt or missing
ForcedLayersAccel: False
IncompatibleExtensions: Unavailable (corrupt or non-existant compatibility.ini 
or extensions.sqlite)
InstallationDate: Installed on 2016-07-22 (0 days ago)
InstallationMedia: Ubuntu-Server 16.04 LTS "Xenial Xerus" - Release amd64 
(20160420.3)
IpRoute:
 default via 192.168.100.1 dev enp24s0 
 169.254.0.0/16 dev enp24s0  scope link  metric 1000 
 192.168.100.0/24 dev enp24s0  proto kernel  scope link  src 192.168.100.152 
 192.168.122.0/24 dev virbr0  proto kernel  scope link  src 192.168.122.1 
linkdown
Locales: extensions.sqlite corrupt or missing
PrefSources: prefs.js
Profiles: Profile0 (Default) - LastVersion=47.0/20160606113944
RunningIncompatibleAddons: False
SourcePackage: firefox
Themes: extensions.sqlite corrupt or missing
UpgradeStatus: No upgrade log present (probably fresh install)
dmi.bios.date: 03/05/2012
dmi.bios.vendor: FUJITSU // Phoenix Technologies Ltd.
dmi.bios.version: Version 1.05
dmi.board.name: FJNB21E
dmi.board.vendor: FUJITSU
dmi.chassis.type: 10
dmi.chassis.vendor: FUJITSU
dmi.modalias: 
dmi:bvnFUJITSU//PhoenixTechnologiesLtd.:bvrVersion1.05:bd03/05/2012:svnFUJITSU:pnT580:pvr:rvnFUJITSU:rnFJNB21E:rvr:cvnFUJITSU:ct10:cvr:
dmi.product.name: T580
dmi.sys.vendor: FUJITSU

** Affects: firefox (Ubuntu)
     Importance: Undecided
         Status: New


** Tags: amd64 apport-bug xenial

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https://bugs.launchpad.net/bugs/1605792

Title:
  firefox fails "profile cannot be loaded"

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