Unfortunately the identical problem persists with all the kernels I tried 
recently:
4.2.0-27-generic
4.4.0-16-generic
4.4.0-17-generic
4.4.0-21-generic
4.5.2-040502-generic
4.6.0-999-generic #201604262201 SMP Wed Apr 27 02:03:00 UTC 2016 x86_64 x86_64 
x86_64 GNU/Linux (from the ppa "daily")

When booted from USB stick the system suspends and wakes up but is
unable to access any filesystems as the stick has moved from /dev/sda to
/dev/sdb. The nvme0n1 device is available before standby an is missing
after. Same goes for all devices on a PCI bus other than 01:

These devices go missing after suspend/standby:
02:00.0 Non-Volatile memory controller: Samsung Electronics Co Ltd NVMe SSD 
Controller (rev 01)
03:00.0 Ethernet controller: Qualcomm Atheros Killer E2400 Gigabit Ethernet 
Controller (rev 10)
04:00.0 Network controller: Intel Corporation Wireless 8260 (rev 3a)

My current guess is an issue with the UEFI/BIOS.

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https://bugs.launchpad.net/bugs/1568703

Title:
  [Alienware Alienware 13 R2] hibernate/resume failure [non-free:
  nvidia_uvm nvidia_modeset nvidia]

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