Possible solution: Dell updated the BIOS for the Dimension E521 model to version 1.1.4 from the original of 1.0.0, and this appears to have fixed the problem.
Here is the BIOS upgrade link for E521 users: http://support.dell.com/support/downloads/download.aspx?c=us&l=en&s=gen&releaseid=R142794&SystemID=DIM_P4_E521&os=BIOSA&osl=en&deviceid=308&devlib=0&typecnt=1&vercnt=3&formatcnt=1&libid=1&fileid=190574 Here is further success stories off of Ubuntu Forums: http://ubuntuforums.org/showthread.php?t=279626&page=8 For now this seems to be the solution, as I've had significantly more time than usual without a USB freeze incident. Thanks everyone. -- USB Devices Freeze Randomly https://launchpad.net/bugs/75045 -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs