Another similar report[1] is not specific to wpasupplicant/ifupdown integration, but seems more like a subtle breakage in the way networking is started on edgy.
[1] https://launchpad.net/distros/ubuntu/+bug/50099 -- No WLAN after boot of 6.10, works with manual ifup/ifdown https://launchpad.net/bugs/69839 -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs