I tested it some more last night( pci=routeirq) and the mouse does freeze after a certain amount of time so this isn't really a solution.
I have a usb hub that is not self powered and I have had same result using the non-self powered usb hub as with using the pci=routeirq boot option. I'll keep looking into it and post another response if I find another possible workarround. Sean. -- Mouse pointer freezes in Dell Dimension E521 / nForce 430 https://launchpad.net/bugs/67734 -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs