I have the same behavior with Microsoft Wireless Optical Desktop 2.20 [Mouse + KBD combo]
uname -r 2.6.17-10-generic I used edgy without problems and only started seeing this behavior 2 days ago. In my case unloading/reloading usbhid is enough to workaround the problem. One thing changed in my setup , I hooked up a Logitech Attack 3 joystick to my system. This is a summary of usb devices: Bus 002 Device 006: ID 0424:223a Standard Microsystems Corp. 8-in-1 Card Reader Bus 002 Device 005: ID 05e3:0605 Genesys Logic, Inc. USB 2.0 Hub [ednet] Bus 002 Device 003: ID 04b8:011b Seiko Epson Corp. Perfection 2400 Photo Bus 002 Device 001: ID 0000:0000 Bus 001 Device 003: ID 046d:c214 Logitech, Inc. Bus 001 Device 002: ID 045e:00e3 Microsoft Corp. Bus 001 Device 001: ID 0000:0000 full listing is attached. I also got: 2 07:03:42 localhost kernel: [ 623.177724] warning: many lost ticks. Nov 2 07:03:42 localhost kernel: [ 623.177728] Your time source seems to be instable or some driver is hogging interupts rip 0x2ac510fd49dc USB interrupts aren't shared: [EMAIL PROTECTED]:~# cat /proc/interrupts CPU0 0: 434593 IO-APIC-edge timer 1: 15 IO-APIC-edge i8042 4: 2 IO-APIC-edge serial 7: 1 IO-APIC-edge parport0 8: 0 IO-APIC-edge rtc 9: 0 IO-APIC-level acpi 14: 20715 IO-APIC-edge ide0 50: 109626 IO-APIC-level ehci_hcd:usb2 58: 97283 IO-APIC-level ohci1394, nvidia 66: 9 IO-APIC-level bttv0, Bt87x audio 74: 6 IO-APIC-level EMU10K1 217: 197748 IO-APIC-level libata, eth0 225: 65033 IO-APIC-level libata 233: 37421 IO-APIC-level ohci_hcd:usb1 NMI: 323 LOC: 436021 ERR: 0 MIS: 0 ** Attachment added: "Full USB listing" http://librarian.launchpad.net/4946575/lsusb.txt -- MS IntelliMouse Optical 1.1A USB stops responding https://launchpad.net/bugs/51054 -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs