Perhaps if the sender has a .BIZ domain that could be a rule?
also, perhaps if the sender's domain ends with a NUMBER, that could be a rule?
You could easily make rules like that.. I don't think that they'd be effective enough to meet the S/O requirements to be a part of the standard ruleset, but they'd be easy enough to write as a rule. It's a pretty non-specific attribute so while it may hit a bunch of spam, it will also likely hit a bunch of nonspam.
The guide gives plenty of information to help you start writing rules:
http://mywpages.comcast.net/mkettler/sa/SA-rules-howto.txt
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