Alfacalcidol is a form of vitamin D. It is converted rapidly in the
liver to the active metabolite, 1,25-dihydroxycholecalciferol
(calcitriol). In the normal situation it controls the intestinal
absorption of calcium and phosphate and plays an important part in the
regulation of bone mineralisation. In chronic renal failure, the
kidneys produce insufficient calcitriol and this leads to
abnormalities of calcium and phosphate metabolism. Oral administration
of alfacalcidol to patients with chronic renal failure compensates for
the reduced production of calcitriol. Consequently, intestinal
malabsorption of calcium and phosphate and the resulting hypocalcaemia
(low blood calcium levels) are improved, thereby reversing the signs
and symptoms of bone disease. Alfacalcidol is also given to provide a
more rapid increase in active vitamin D and hence calcium, in people
with various bone diseases. As this form of vitamin D only requires
one conversion to become calcitriol, it provides a quicker response
than giving normal dietary vitamin D. supplements.

http://www.netdoctor.co.uk/medicines/100001925.html

On Fri, Aug 28, 2009 at 1:03 PM, Kirsteen
Wright<[email protected]> wrote:
> Sorry this off yopic but I really don't know where else to ask. I believe
> we're probably all short of Vit D especially here in Scotland. I'd ordered
> some supplements (Biolife Vit D3) and started taking them. I persuaded my
> doc to test my blood levels (no idea what test they actually did) and he
> agreed I wasmarginally low. so prescribed One-Alpha 0.25mcg alfacalcidol.
> now I may just be highly suspicious of the medical profession but this looks
> more like a medicine than a drug and I'm finding it very hard to get any
> info on it. Does anyone know anything about it?
>
> thanks
> Kirsteen
>


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