Re: [Open Babel] making wedge & hashed bonds

Hi! Thank you for your reply. If we use "add hydrogens (make explicit)" we have effectively all the hydrogens in the .mol file. In our example, hydrogen of the stereocenter appear with hash bond (6) but the wedge bond (normaly 1) is not specified (0). Do we have to change the SMILE descriptor?

[Open Babel] Why is it so important to humanize antibodies?

In antibody based research, it's necessary to humanize antibodies. The purpose of antibody humanization is reducing the immunogenicity of monoclonal antibodies derived from xenogeneic sources (commonly rodent) and improving their acti