(and especially those negative
values) should be treated with something like the M3 likelihood method.
Regards,
Rupert
Rupert Austin, PhD
Senior Scientist
BAST Inc Limited
Holywell Park
Ashby Road
Loughborough, LE11 3AQ, UK
From: owner-nmus...@globomaxnm.com [mailto:owner-nmus
(3)” includes time dependent covariates. Rather
worryingly, I don’t think NONMEM will trap this problem since I have fallen
foul of it with no resulting NONMEM warnings, and I have no idea what the
consequences are for the resulting NONMEM run and results.
Rupert
Rupert Austin, PhD
