Hyewon,
Sorry -- I just realized that EFF is not the drug effect but 1-drug
effect so that it has a value of 1 when AUC is zero. Please ignore my
remarks about EFF being zero when AUC is zero in my comments below and
consider this code to describe the effect of AUC on hazard:
HAZNOW=LAMD*AL
Dear all,
Thank you for your thoughtful advice.
It helps a lot.
Hyewon.
On Thu, Mar 24, 2011 at 1:53 AM, Nick Holford wrote:
> Hyewon,
>
> Sorry -- I just realized that EFF is not the drug effect but 1-drug effect
> so that it has a value of 1 when AUC is zero. Please ignore my remarks about
>
Dear NonMEM users,
I am constructing a transduction model to capture disease onset time-delay
using NonMEM. Because
I need to use too mamy compartments (means too much ODE) to handle this delay,
I want to use DoLoop
to save a little room. But I can not find a way to use it in $DES block. The
Dear Liu,
In nonmem you can not define differential equations through a loop; each
has to be explicitly written out.
However, I notice that you have the same rate of transit among all of
your (transit) compartments.
Therefore, an analytical solution would be the most efficient way of
solving
