Dear all,
Dropping in a little late in the game all I can say is this:
Shame on all you great minds for reinventing your own wisdom :>)
Most of the content in the current thread has already been discussed in
an earlier thread:
http://www.mail-archive.com/nmusers@globomaxnm.com/msg01271.ht
Dear Jakob and all,
In this thread, Mats clearly indicated Eta is assumed normal distributed.
But, others have said differently.
I wonder which statement is correct?
From: "Ribbing, Jakob"
To: nmusers
Sent: Tue, June 1, 2010 3:10:44 AM
Subject: RE: [N
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1. "your post is too long":
One potential problem you may encounter with the nmusers list is by
sending ".doc" of ".pdf" files or if you are in the habit of carrying
along all past threads in your response. Our server has a limit on the
length of the emails you may submit and these application
I don't recall the context in which this was said, but, I remember
Stuart Beal saying something to the effect of "the assumption of
normality of distributions is not a strict one and that NONMEM works
quite well as long as the distributions are relatively symmetrical". I
will leave the interpretat
Dear Ethan,
I am not 100% on exactly who said what in this thread and do not want to
put my words in anyone else's mouth, but I think we can all agree on
this:
* In simulation mode NONMEM assumes a normal distribution of etas
* In estimation mode omega can be seen as an estimate of
