Bob,
Thanks for pointing out that one cannot use NONMEM to describe the
Cauchy distribution. Presumably this explains why we dont seem to have
many physicists on nmusers :-). The normal assumption for NONMEM
simulation seems to be well accepted so no simulated spectral lines I'm
afraid.
How
Dear Ethan,
If you want to try a nonparametric method, you can do that already in
NONMEM, using $NONPARAMETRIC. If you worry about distributional assumptions
of your ETAs having an impact on your model or your model derived decisions,
this is often a good procedure. Results that agree between $
I'd like to interject a slightly different point of view to the distributional
assumption question here.
When I hear people speak in terms of the “distribution assumptions of some
estimation method” I think its easy for people to jump to the conclusion that
the normal distribution assumptio
