turday, 11 May 2019 4:33 PM
To: Bill Denney
Cc: nmusers
Subject: Re: [NMusers] bootstrap
Dear Nick and Bill,
Thank you for your answers, and please apologize me for din´t give you
information about my model.
I share with you part of my code as well as some results. My model corresponds
t
Dear Nick and Bill,
Thank you for your answers, and please apologize me for din´t give you
information about my model.
I share with you part of my code as well as some results. My model
corresponds to QSS with constant Rtot approximation of TMDD The
parameter estimates obtained with this model ar
Hi Niurys,
The simplest method to ensure a good bootstrap is often to simplify the data
file by removing rows that should not be used for the modeling before
running the bootstrap. Notably, if you exclude an entire subject either
based on the ID column or another column, usually the boostrap will
, PhD
pascal.gir...@merckgroup.com
Head of Modeling & Simulation - Oncology
Global Exploratory Medicine
Merck Serono S.A. · Geneva
Tel: +41.22.414.3549
Cell: +41.79.508.7898
From:
To: "Mats Karlsson"
Cc: ,
Date: 14/02/2013 10:33
Subject: RE: [NMusers] Boots
4714003
From: anubha_gu...@eisai.net [mailto:anubha_gu...@eisai.net]
Sent: 14 February 2013 10:07
To: Mats Karlsson
Cc: jos.lomme...@merck.com; nmusers@globomaxnm.com
Subject: RE: [NMusers] Bootstrap, re-using inital model run results
Dear Mats
My question is more related to boot
Date: 14/02/2013 08:50
Subject:RE: [NMusers] Bootstrap, re-
Dear Jos,
If you haven't run the original model (indicated by absence of lst-file with
the same prefix) psn will run it before the bootstrap. If you have run it,
PsN will not rerun it. It will use the results in the corresponding lst
file. If you have run it and called it something else, you co
Hi Pierre-Olivier,
Thank you for your suggestion that has worked perfectly ;-)
Many thanks
Neil
From: Tremblay, Pierre-Olivier [mailto:potremb...@pharmanet-i3.com]
Sent: 05 October 2012 15:20
To: Attkins, Neil
Subject: RE: [NMusers] Bootstrap histograms in R
Hi Neil,
We don't have the
.
-Original Message-
From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On
Behalf Of Leonid Gibiansky
Sent: jueves, 22 de diciembre de 2011 7:08
To: Brogren Jacob
Cc: nmusers@globomaxnm.com
Subject: Re: [NMusers] Bootstrap in combination with PRIOR?
Jacob,
Bootstrap
Jacob,
Bootstrap procedure vary only the new data. The information in priors is
still the same. Therefore, results will be as dependent on the priors as
the parameter estimates of the final model. When the priors are strong
(informative) it would require a lot of new data to move the parameter
I do not think that bootstrap mean is a useful statistics. Median of the
bootstrap distribution could/should be compared with the final-model
point estimates. Precision of the parameter estimates can be evaluated
as a 95% confidence interval defined as an interval between 2.5 and 97.5
percentil
Varsha,
Congratulations on discovering how to use a bootstrap to evaluate the
distribution of your model parameter estimates.
The bootstrap mean is probably a more robust estimate of the true value
of the parameter than the value estimated from the original data. I
prefer to report the boots
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