turday, 11 May 2019 4:33 PM
To: Bill Denney
Cc: nmusers
Subject: Re: [NMusers] bootstrap
Dear Nick and Bill,
Thank you for your answers, and please apologize me for din´t give you
information about my model.
I share with you part of my code as well as some results. My model corresponds
t
27;t help, giving more info will help. (What tool are you using
> for bootstrap? What command line are you running? Can you share the model
> and a snippet of the data?)
>
> Thanks,
>
> Bill
>
> -Original Message-
> From: owner-nmus...@globomaxnm.com On Beh
?)
Thanks,
Bill
-Original Message-
From: owner-nmus...@globomaxnm.com On Behalf
Of Niurys.CS
Sent: Friday, May 10, 2019 12:17 PM
To: nmusers
Subject: [NMusers] bootstrap
Dear nmusers,
I have a big doubt. When I used the bootstrap to evaluate my model, I had
some bugs. In my code I
Dear nmusers,
I have a big doubt. When I used the bootstrap to evaluate my model, I
had some bugs. In my code I use IGNORE statements based on FLAGS for
some outliers. I don't know if I remove these IGNORE statements, the
bootstrap will run well. Can you give me some suggestions???
Regards
, PhD
pascal.gir...@merckgroup.com
Head of Modeling & Simulation - Oncology
Global Exploratory Medicine
Merck Serono S.A. · Geneva
Tel: +41.22.414.3549
Cell: +41.79.508.7898
From:
To: "Mats Karlsson"
Cc: ,
Date: 14/02/2013 10:33
Subject: RE: [NMusers] Boots
4714003
From: anubha_gu...@eisai.net [mailto:anubha_gu...@eisai.net]
Sent: 14 February 2013 10:07
To: Mats Karlsson
Cc: jos.lomme...@merck.com; nmusers@globomaxnm.com
Subject: RE: [NMusers] Bootstrap, re-using inital model run results
Dear Mats
My question is more related to boot
Date: 14/02/2013 08:50
Subject:RE: [NMusers] Bootstrap, re-
nt: 14 February 2013 08:29
To: nmusers@globomaxnm.com
Subject: [NMusers] Bootstrap, re-using inital model run results
Hi
I would like to ask to NONMEM community whether it is possible to re-use the
results of a nonmem model run when starting bootstrapping.
As I understand, a bootstrap run usi
Hi
I would like to ask to NONMEM community whether it is possible to re-use the
results of a nonmem model run when starting bootstrapping.
As I understand, a bootstrap run using PsN starts with a single calculation of
the model of interest and data set as is. Once this initial model run
has comp
Hi Mike,
Great, many thanks for your suggestions, I will definitely try them out.
Many thanks
Neil
From: Smith, Mike K [mailto:mike.k.sm...@pfizer.com]
Sent: 06 October 2012 11:22
To: 'sebastian.frec...@uk-koeln.de'; Attkins, Neil; 'nmusers@globomaxnm.com'
Subject: Re: AW:
echen, Dr. Sebastian [mailto:sebastian.frec...@uk-koeln.de]
Sent: Saturday, October 06, 2012 05:35 AM
To: 'Attkins, Neil' ; nmusers@globomaxnm.com
Subject: AW: [NMusers] Bootstrap histograms in R
Hey Neil
If you would like to save your graphics in a pdf you could also add the
following
us...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] Im
Auftrag von Attkins, Neil
Gesendet: Freitag, 5. Oktober 2012 16:33
An: Tremblay, Pierre-Olivier; nmusers@globomaxnm.com
Betreff: RE: [NMusers] Bootstrap histograms in R
Hi Pierre-Olivier,
Thank you for your suggestion that
Hi Pierre-Olivier,
Thank you for your suggestion that has worked perfectly ;-)
Many thanks
Neil
From: Tremblay, Pierre-Olivier [mailto:potremb...@pharmanet-i3.com]
Sent: 05 October 2012 15:20
To: Attkins, Neil
Subject: RE: [NMusers] Bootstrap histograms in R
Hi Neil,
We don't have the
Hi
I have just run a bootstrap analysis on my final Pop PK model using NONMEM 7.2
with PDx-Pop 5. My model has 7 Thetas in it and when I come to evaluate the
output from the bootstrap in R the Theta histograms are plotted in a 3x2 matrix
in an R window, and the plot for Theta 7 seems to overwri
.
-Original Message-
From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On
Behalf Of Leonid Gibiansky
Sent: jueves, 22 de diciembre de 2011 7:08
To: Brogren Jacob
Cc: nmusers@globomaxnm.com
Subject: Re: [NMusers] Bootstrap in combination with PRIOR?
Jacob,
Bootstrap
Jacob,
Bootstrap procedure vary only the new data. The information in priors is
still the same. Therefore, results will be as dependent on the priors as
the parameter estimates of the final model. When the priors are strong
(informative) it would require a lot of new data to move the parameter
Dear nmusers,
Merry Holiday! (you may change the variable 'Holiday' to an arbitrary value)
First, accept my humble excuse - I can't share any code for this example.
I'm assessing a model where $PRIOR is used to stabilize the fit of an 'old'
model to sparse data using NONMEM. It seems to be the
I do not think that bootstrap mean is a useful statistics. Median of the
bootstrap distribution could/should be compared with the final-model
point estimates. Precision of the parameter estimates can be evaluated
as a 95% confidence interval defined as an interval between 2.5 and 97.5
percentil
Varsha,
Congratulations on discovering how to use a bootstrap to evaluate the
distribution of your model parameter estimates.
The bootstrap mean is probably a more robust estimate of the true value
of the parameter than the value estimated from the original data. I
prefer to report the boots
Group:
I have bootstrap analysis (my first) parameter estimates and model
parameters. The PDxPOP/NONMEM manual I have does not provide
any guidance as to how I can statistically compare these two (or do I
need to?). I also have histograms for the thetas in bootstrap analysis.
I can make some vi
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