Re: [NMusers] Mixture model simulation

2013-05-07 Thread Paul Hutson
ox 591 75124 Uppsala Phone: +46 18 4714105 Fax + 46 18 4714003 -Original Message- From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of Paul Hutson Sent: 07 May 2013 17:32 To: nmusers@globomaxnm.com Subject: [NMusers] Mixture model simulation Dear Users: I n

RE: [NMusers] Mixture model simulation

2013-05-07 Thread E.Olofsen
ht be different for the subgroups? Erik From: owner-nmus...@globomaxnm.com [owner-nmus...@globomaxnm.com] on behalf of Paul Hutson [prhut...@pharmacy.wisc.edu] Sent: Tuesday, May 07, 2013 5:31 PM To: nmusers@globomaxnm.com Subject: [NMusers] Mixture

RE: [NMusers] Mixture model simulation

2013-05-07 Thread Mats Karlsson
aul Hutson Sent: 07 May 2013 17:32 To: nmusers@globomaxnm.com Subject: [NMusers] Mixture model simulation Dear Users: I note the Jan 26, 2013 response to Nick Holford's query about results from the use of the $MIX mixture model for simulation. I have created a data set of N=100 subjects usin

Re: [NMusers] Mixture model simulation

2013-05-07 Thread Leonid Gibiansky
Well, it was the wrong guess, MIXNUM should work -- Leonid Gibiansky, Ph.D. President, QuantPharm LLC web:www.quantpharm.com e-mail: LGibiansky at quantpharm.com tel:(301) 767 5566 should it be IF(MIXEST.EQ.2) Z=0 for the fitting run? On 5/7/2013 1

Re: [NMusers] Mixture model simulation

2013-05-07 Thread Leonid Gibiansky
should it be IF(MIXEST.EQ.2) Z=0 for the fitting run? -- Leonid Gibiansky, Ph.D. President, QuantPharm LLC web:www.quantpharm.com e-mail: LGibiansky at quantpharm.com tel:(301) 767 5566 On 5/7/2013 11:31 AM, Paul Hutson wrote: Dear Users: I note t

[NMusers] Mixture model simulation

2013-05-07 Thread Paul Hutson
Dear Users: I note the Jan 26, 2013 response to Nick Holford's query about results from the use of the $MIX mixture model for simulation. I have created a data set of N=100 subjects using R to randomly distribute their covariates, both continuous and categorical. I then ran the following sim

RE: [NMusers] Mixture model simulation

2013-01-25 Thread Bauer, Robert
sage- From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of Nick Holford Sent: Friday, January 25, 2013 4:00 PM To: nmusers Subject: Re: [NMusers] Mixture model simulation Tom (and others), Thanks for your replies and suggestions. I've looked at the behaviour

RE: [NMusers] Mixture model simulation

2013-01-25 Thread E.Olofsen
[n.holf...@auckland.ac.nz] Sent: Friday, January 25, 2013 10:00 PM To: nmusers Subject: Re: [NMusers] Mixture model simulation Tom (and others), Thanks for your replies and suggestions. I've looked at the behaviour of both MIXNUM and MIXEST. As Tom stated it seems that MIXNUM describe

Re: [NMusers] Mixture model simulation

2013-01-25 Thread Nick Holford
I am not certain what value MIXEST will have for each individual. Best wishes, Tom Ludden -Original Message- From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of Nick Holford Sent: Friday, January 25, 2013 2:51 AM To: nmusers Subject: [NMusers] Mixture

R: [NMusers] Mixture model simulation

2013-01-25 Thread Roberto Gomeni
...@globomaxnm.com] Per conto di Nick Holford Inviato: venerdì 25 gennaio 2013 09:51 A: nmusers Oggetto: [NMusers] Mixture model simulation Hi, I've been puzzled by the behaviour of NONMEM when trying to simulate with a mixture model. The data file has 1000 subjects. I simulate 100 times (see control s

RE: [NMusers] Mixture model simulation

2013-01-25 Thread E.Olofsen
, 2013 9:50 AM To: nmusers Subject: [NMusers] Mixture model simulation Hi, I've been puzzled by the behaviour of NONMEM when trying to simulate with a mixture model. The data file has 1000 subjects. I simulate 100 times (see control stream below). The overall number of subjects with MIXEST of 1

[NMusers] Mixture model simulation

2013-01-25 Thread Nick Holford
Hi, I've been puzzled by the behaviour of NONMEM when trying to simulate with a mixture model. The data file has 1000 subjects. I simulate 100 times (see control stream below). The overall number of subjects with MIXEST of 1 is 45%. There are no simulated values of 99. All values are either 1