[NMusers] FW: Pharmacometrics Opportunities at Janssen in US (Johnson & Johnson)

Forward on behalf of Honghui Zhou: Dear Colleagues, We currently have two immediate pharmacometrics openings in Clinical Pharmacology and Pharmacometrics at Janssen (Johnson & Johnson) in US (Spring House, PA or Raritan, NJ). Please visit the JNJ careers site for current openings or follow th

[NMusers] FW: ASA Statement Released Today

jnj.com> ~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~* From: asam...@amstat.org [mailto:asam...@amstat.org] Sent: Monday, March 07, 2016 11:15 AM To: Hu, Chuanpu [JRDUS] Subject: ASA Statement Released Today [Image removed by sender.]<http://www.amstat.org> ASA Statement Released Today Dea

[NMusers] RE: Is it reasonable to add covarite to PD parameters kin or kout?

Hello - The following should be helpful: Approaches to handling pharmacodynamic baseline responses Chantaratsamon Dansirikul * Hanna E. Silber * Mats O. Karlsson J/PK/PD 2008 :) Chuanpu From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of Peiming Ma Sent: Mond

[NMusers] Summer Intern Position at Johnson & Johnson - PA - USA

Dear all, The Pharmacological and Translational Modeling group in Model Based Drug Development, Janssen Research & Development, LLC, located in Spring House, PA, is looking for an intern this summer. This intern will work in a congenial group having pharmacological as well as statistical expert

[NMusers] Implementing multivariate normal cdf

Hello Colleagues, I thought the multivariate normal cumulative distribution function would be available in NM7.3 but could not find it. Would appreciate ideas on how to implement it. Thanks in advance, Chuanpu ~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~* Chuanpu Hu, Ph.D. Scientifi

[NMusers] PK/PD Modeling Job Opportunities at Johnson & Johnson

Scientific Director - PK/PD Modeling Job at Johnson & Johnson (8896141109) Date: Dec 03, 2014 Location: Spring House, PA, US Description Janssen Research & Development, L.L.C., a Johnson & Johnson company, is recruiting a Scientific Director of PK/PD Modeling to be located in Spring House, PA.

[NMusers] PK/PD Modeling Position at Johnson & Johnson

Associate Scientific Director, PK/PD Modeling-9659140429 Description Janssen Research & Development, L.L.C., a Johnson & Johnson company, is recruiting an Associate Scientific Director to be located in Spring House, PA. Janssen Research & Development, L.L.C. develops treatments that improve th

RE: [NMusers] PHI inverse?

.” Would that mean that PHI computation in NONMEM has an accuracy of 1e-05? Best regards, Chuanpu From: Ron Keizer [mailto:ron.kei...@farmbio.uu.se] Sent: Sunday, May 13, 2012 2:00 PM To: Hu, Chuanpu [JRDUS] Cc: nmusers@globomaxnm.com Subject: Re: [NMusers] PHI inverse? hi Chuanpu, i

[NMusers] PHI inverse?

Dear Colleagues, It appears that NM7 has the PHI() function but not its inverse. Before NM7 was available people used approximations of PHI, e.g., to handle BQL. Does anyone know of any similarly implementable approximations of the inverse function of PHI? Thank you, Chuanpu ~*~*~*~*~*

RE: [NMusers] NPDE for parent and metabolite data

Dear Ayyappa, My reading of the methodology is that NPDE are independent standard normally distributed regardless of design groups, so there is no problem in plotting NPDE with and without strata since they just become different diagnostics. There will be some overlapping information, e.g., if