[Freesurfer] good news and bad news

2005-10-21 Thread Bruce Fischl
Hi All, I'll start with the good: thanks to Anders Dale (UCSD), Howard Pinsky (CorTechs) and Christian Euseman (MGH), we have finally signed an open source agreement for FreeSurfer. We will be posting a "read-only" tarball on the website in the next couple of weeks, and anyone is free to down

[Freesurfer] Anatomical parcellation in patients

2005-10-21 Thread Goulven Josse
Dear freesurfers, We are trying to analyse data from patients who had an early stroke. I did one automated parcellation (Fischl et al, 2004) in a patient with a peri-ventricular enlargement associated with a large overall atrophy of the injured hemisphere. I was pleased to find out that, even i

RE: [Freesurfer] Anatomical parcellation in patients

2005-10-21 Thread Bagnato, Francesca (NIH/NINDS)
Dear Josse and all: Before posing the parcellation problem with respect to patients with cortical lesions, I was wondering to ask if anybody has a clue on how the segmentation of the cortex/WM might work in patients with juxtacortical/cortical lesions. In other words: how the drop of the signal gi

Re: [Freesurfer] Anatomical parcellation in patients

2005-10-21 Thread Bruce Fischl
Hi Goulven, we've applied it to tons of Alzheimer's cases and other similar ones with huge ventricles, and it's usually no problem. Particularly in the new (not quite officially released) version in which ventricular size is normalized out. cheers, Bruce On Fri, 21 Oct 2005, Goulven Josse

RE: [Freesurfer] Anatomical parcellation in patients

2005-10-21 Thread Bruce Fischl
Hi Francesca, this is tough to answer as it depends on the exact location of the cortical lesion, and the thickness of the underlying white matter. As you know, we have done a fair number of MS subjects, so in general it's okay, but I can certainly imagine scenarios in which things fail. sor

RE: [Freesurfer] Anatomical parcellation in patients

2005-10-21 Thread Bruce Fischl
Hi Francesca, we haven't done a ton of stuff at 3T, and no MS that I'm aware of (although there maybe people at MGH doing so that I don't know about). Bruce On Fri, 21 Oct 2005, Bagnato, Francesca (NIH/NINDS) wrote: Thanks Bruce, I was wondering if you have noted differences between 1.5 a

RE: [Freesurfer] Anatomical parcellation in patients

2005-10-21 Thread Bagnato, Francesca (NIH/NINDS)
Thanks Bruce, I was wondering if you have noted differences between 1.5 and 3T images as far as it concerns this issue. Indeed, the MS cortical lesions are definitely visible on a 3T anatomical RMI but barely detectable in 1.5T SPGRs. Thanks, -francesca Francesca Bagnato, MD NIB-NINDS-NIH 10 C