Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-07 Thread Bruce Fischl
if you can On Mon, 7 Oct 2013, Caspar M. Schwiedrzik wrote: Hi Bruce, it sounds very possible that the bright spots (which are gadolinium-enhanced blood vessels) cause the problem. I guess I will have to remove them. Does it make sense to manually delete them from brain.mgz? Caspar 2013/10/7

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-07 Thread Caspar M. Schwiedrzik
Hi Bruce, it sounds very possible that the bright spots (which are gadolinium-enhanced blood vessels) cause the problem. I guess I will have to remove them. Does it make sense to manually delete them from brain.mgz? Caspar 2013/10/7 Bruce Fischl > Hi Caspar > > I'm not sure what to tell you. Th

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-07 Thread Bruce Fischl
Hi Caspar I'm not sure what to tell you. There are bright spots and rings out near the pial surface that are probably part of your problem, and the images even in the zoom look really inhomogenous. I don't think we ever have to add thousands of control points, but I have no experiences with NH

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Caspar M. Schwiedrzik
Hi Bruce, sorry, I meant to say that data is conformed. It is primate data. I am having trouble with this particular data set only; the other ones are at the same resolution and worked fine. I am attaching another screenshot to show that the control points unfortunately do not solve the problem. Se

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Bruce Fischl
Hi Caspar, that's probably part of the problem. Is this human data? If you actually run it at 1mm (conforming it) does it work better? Bruce On Thu, 3 Oct 2013, Caspar M. Schwiedrzik wrote: It is originally 0.5x0.5x0.5 mm but we are pretending it's 1x1x1 mm. Caspar 2013/10/3 Bruce Fisch

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Caspar M. Schwiedrzik
It is originally 0.5x0.5x0.5 mm but we are pretending it's 1x1x1 mm. Caspar 2013/10/3 Bruce Fischl > what resolution? > > On Thu, 3 Oct 2013, Caspar M. Schwiedrzik wrote: > > This was a fairly regular MPRAGE, unfortunately not very well optimized >> for >> contrast. However, the main issue see

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Bruce Fischl
what resolution? On Thu, 3 Oct 2013, Caspar M. Schwiedrzik wrote: This was a fairly regular MPRAGE, unfortunately not very well optimized for contrast. However, the main issue seems to be that the data were acquired with a surface coil here. That made some of the brain extremely bright (close to

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Caspar M. Schwiedrzik
This was a fairly regular MPRAGE, unfortunately not very well optimized for contrast. However, the main issue seems to be that the data were acquired with a surface coil here. That made some of the brain extremely bright (close to the coil) and some of the brain pretty dark (far away from the coil)

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Bruce Fischl
h. Can you tell us more about the acquisition? On Thu, 3 Oct 2013, Caspar M. Schwiedrzik wrote: the white matter is mostly between 100 and 110 in these regions. at least in the center of the wm, the voxels are almost all 110. caspar 2013/10/3 Bruce Fischl is the WM in those region

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Caspar M. Schwiedrzik
the white matter is mostly between 100 and 110 in these regions. at least in the center of the wm, the voxels are almost all 110. caspar 2013/10/3 Bruce Fischl > is the WM in those regions already close to 110? No, there is no way to > normalize GM intensity (it has too much biological variabil

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Bruce Fischl
is the WM in those regions already close to 110? No, there is no way to normalize GM intensity (it has too much biological variability over the brain) On Thu, 3 Oct 2013, Caspar M. Schwiedrzik wrote: > Thanks, Bruce. The problem is fairly extensive. There is no way to do > normalize grey matte

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Caspar M. Schwiedrzik
Thanks, Bruce. The problem is fairly extensive. There is no way to do normalize grey matter intensity (the white surface looks pretty good)? Caspar On Thursday, October 3, 2013, Bruce Fischl wrote: > Hi Caspar > > try putting control points in the white matter where the pial surface > doesn't get

Re: [Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Bruce Fischl
Hi Caspar try putting control points in the white matter where the pial surface doesn't get out far enough. cheers Bruce On Thu, 3 Oct 2013, Caspar M. Schwiedrzik wrote: > Hi Freesurfer Experts, > I am working on a fairly noisy and inhomogeneous MPRAGE T1 and I am having > trouble getting the p

[Freesurfer] trouble with pial surface in v5.1

2013-10-03 Thread Caspar M. Schwiedrzik
Hi Freesurfer Experts, I am working on a fairly noisy and inhomogeneous MPRAGE T1 and I am having trouble getting the pial surface to go all the way through the grey matter. Please see screenshot attached. These data were acquired with a surface coil and the grey matter varies a lot in intensity. I