Re: [Freesurfer] thickness maps: FDR versus Monte Carlo - different results

2010-02-01 Thread Stefan Ehrlich
or cluster-mass method within freesurfer? Thank you so much! Stefan Message: 1 Date: Fri, 29 Jan 2010 14:57:34 -0800 From: Don Hagler Subject: Re: [Freesurfer] thickness maps: FDR versus Monte Carlo - different results To: Doug Greve Cc: freesurfer maillist Message-ID: Content-Type: text

Re: [Freesurfer] thickness maps: FDR versus Monte Carlo - different results

2010-01-29 Thread Don Hagler
500 > From: gr...@nmr.mgh.harvard.edu > To: dhagle...@hotmail.com > CC: freesurfer@nmr.mgh.harvard.edu > Subject: Re: [Freesurfer] thickness maps: FDR versus Monte Carlo - > different results > > Don, why do you say that .05 is too liberal? We use a simulation-based > test

Re: [Freesurfer] thickness maps: FDR versus Monte Carlo - different results

2010-01-29 Thread Donna Dierker
FDR is NOT more conservative than cluster-based methods, in general. The smoother the data, the more conservative FDR is. In my experience with surface-based data, FDR has been less sensitive than cluster-based methods -- perhaps because my data was very smooth. > Stefan Brauns wrote: > >> W

Re: [Freesurfer] thickness maps: FDR versus Monte Carlo - different results

2010-01-29 Thread Douglas N Greve
e multiple comparison > corrected p value, for which you would usually use 0.05. > > > Date: Fri, 29 Jan 2010 10:02:45 -0500 > From: stefan.bra...@googlemail.com > To: Freesurfer@nmr.mgh.harvard.edu > Subject

Re: [Freesurfer] thickness maps: FDR versus Monte Carlo - different results

2010-01-29 Thread Don Hagler
nd is the multiple comparison corrected p value, for which you would usually use 0.05. Date: Fri, 29 Jan 2010 10:02:45 -0500 From: stefan.bra...@googlemail.com To: Freesurfer@nmr.mgh.harvard.edu Subject: [Freesurfer] thickness maps: FDR versus Monte Carlo - different results Hi there, we are s

Re: [Freesurfer] thickness maps: FDR versus Monte Carlo - different results

2010-01-29 Thread Douglas N Greve
These results look reasonable given what each method is doing. The FDR blob is there because it is very bright (significant). It is lost in the cluster-wise correction because it is small, and the cluster-wise correction does not care how significant something is as long as it meets threshold.