Re: [Freesurfer] subfield algorithm and subject intensity differences

2013-06-08 Thread Joshua Lee
That is interesting and good to know. Thanks. I am looking for a reference that provides validation metrics on the Van Leemput (2010) method as implemented in Freesurfer. To your knowledge, is there such a reference? Best, Joshua On Fri, Jun 7, 2013 at 12:49 PM, Juan Eugenio Iglesias < igles.

Re: [Freesurfer] subfield algorithm and subject intensity differences

2013-06-07 Thread Joshua Lee
Thanks Bruce and Eugenio, Suppose I had two identical images of a subject, but in one image I reduced the contrast of internal lamina while leaving the rest of the image intact...just removing internal intensity differences, but leaving the outer boundary contrast intact. Would the images result

Re: [Freesurfer] subfield algorithm and subject intensity differences

2013-06-07 Thread Juan Eugenio Iglesias
Dear Josh, at this point, and given that the boundaries between these subfields cannot really be seen in 1mm T1 scans, the algorithm assumes that all the subfields other than fimbria and fissure share the same image intensity properties. Therefore, using your own words: "depend only on outward bo

Re: [Freesurfer] subfield algorithm and subject intensity differences

2013-06-07 Thread Bruce Fischl
Hi Josh it depends on intensity differences if it can find them as well as boundary/geometry. cheers Bruce On Fri, 7 Jun 2013, Joshua Lee wrote: > I'm trying to understand Leemput's subfield algorithm better as implemented > in Freesurfer. Does the algorithm make use of intensity differences

[Freesurfer] subfield algorithm and subject intensity differences

2013-06-07 Thread Joshua Lee
I'm trying to understand Leemput's subfield algorithm better as implemented in Freesurfer. Does the algorithm make use of intensity differences in the internal hippocampal lamina from the subject's T1 image to warp meshes and assign subfield probabilities? Or does it depend only on outward boundari