[Freesurfer] Recent paper on FreeSurfer reliability

2012-06-28 Thread Ed Gronenschild
Dear Bruce, Doug, Nick, and other co-workers, As authors of the recent paper “The effects of FreeSurfer version, workstation type, and Macintosh operating system version on anatomical volume and cortical thickness measurements” we would like to take the opportunity to respond to the numerous

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread Gregory Kirk
bottom line is can we trust freesurfer cortical thickness results and a recent paper my group published seems to give very strong positive answer to the question. paper - cortical thinning in psychopathy, it's on the wiki publication list. All of the areas reported overlap with the areas that ha

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread Gabriele Fariello
Hi Bruce et al, I may be late to the discussion, but wanted to share some insights given that we've had some headaches trying to get identical results on presumptively identical systems for FreeSurfer and other tools, I wanted to add my two cents. Ultimately, of course, the systems were not 100% i

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread Nick Schmansky
Mike, I have run such tests in the past (which showed about 2-3% variability in hippo volume due to randomness) and Doug has done similar tests, but admittedly running a large scale analysis and showing the results on a wiki page would be useful. Something like running our Buckner40 and/or ADNI60

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread Nick Schmansky
Peter, Thanks for this info. The Mac OS versions compared in the paper were 10.5 and 10.6 (Leopard and Snow Leopard). One of the major changes between these two versions was the switch from a 32b kernel to a 64b kernel (whereas Snow Leopard and Lion both use a 64b kernel). I havent been able to

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread SHAHIN NASR
Please post it on PLoS One homepage. According to the policies of this journal, you are allowed to respond to each paper directly on the same page as the article. You don't need to submit it as a paper and won't go through a review process. On Wed, Jun 20, 2012 at 10:28 AM, Peter J. Molfese < pm

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread Bruce Fischl
Nick might have, not sure. Are you volunteering Mike :) On Wed, 20 Jun 2012, Michael Harms wrote: > > I'm curious: For comparison to the results in that paper, has anyone > quantified the variability that results when one runs the same FS > version repeatedly on the same subject, but with a diffe

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread Michael Harms
I'm curious: For comparison to the results in that paper, has anyone quantified the variability that results when one runs the same FS version repeatedly on the same subject, but with a different random seed each time? That is, how much of the difference is related to math libraries vs. intrinsic

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread Bruce Fischl
p.s. I should add that we've known about this effect for a while (as the authors in the paper state), but haven't had the time to track it down. Since it's an avoidable source of variance (by controlling what computers you run the analysis on), it's lower on our list of priorities than other im

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread Bruce Fischl
Hi Peter thanks for the info. Feel free to post this on one of the *many* blogs howling for our blood :) I think that the effects in the paper reflect default floating point settings in gcc on 32-bit vs. 64-bit, although we haven't really investigated as it doesn't seem like a wise use of limi

Re: [Freesurfer] Recent paper on FreeSurfer reliability

2012-06-20 Thread Peter J. Molfese
We run things on an Xgrid cluster that is now a mixture of Macs running Snow Leopard (10.6.8) and Lion (10.7.x). We found the results given from asegstats2table and aparcstats2table are identical after running 100 subjects on both Mac OS X 10.7.4 and 10.6.8 with Freesurfer 5.1. I also ran a few

[Freesurfer] Recent paper on FreeSurfer reliability

2012-06-02 Thread Ed Gronenschild
Hi, The paper entitled “The Effects of FreeSurfer Version, Workstation Type, and Macintosh Operating System Version on Anatomical Volume and Cortical Thickness Measurements”, PLoSONE, Vol 7(6), e38234 (2012) may be of interest to all of you. It can be found at: http://dx.plos.org/10.1371/journ