Re: [Freesurfer] Multiple Comparison Question for surface-based analyses

2016-10-28 Thread Douglas Greve
On 10/17/16 2:16 AM, Ajay Kurani wrote: Hi Doug, I had some additional questions regarding multiple comparisons in Freesurfer. 1) Do you correct the left and right hemispheres separately or combine both together for muliple comparison correction? We correct each hemi independently and the

Re: [Freesurfer] Multiple Comparison Question for surface-based analyses

2016-10-16 Thread Ajay Kurani
Hi Doug, I had some additional questions regarding multiple comparisons in Freesurfer. 1) Do you correct the left and right hemispheres separately or combine both together for muliple comparison correction? 2) Say you are testing multiple contrasts in your model: A > B, A< B etc. Do you correct

Re: [Freesurfer] Multiple Comparison Question for surface-based analyses

2016-08-03 Thread Douglas Greve
On 8/3/16 3:45 AM, Ajay Kurani wrote: Hi Doug, Thank you very much for your update regarding this issue. 1)Just curious, will LGI be included in this report as this is another analysis of interest? I was not planning to. The 809 subjects that I used for thickness do not have lGI run on th

Re: [Freesurfer] Multiple Comparison Question for surface-based analyses

2016-08-03 Thread Ajay Kurani
Hi Doug, Thank you very much for your update regarding this issue. 1)Just curious, will LGI be included in this report as this is another analysis of interest? 2)As for the cortical thickness I originally used 15mm in the analysis so based on your email I think using 5-10mm may be more prudent

Re: [Freesurfer] Multiple Comparison Question for surface-based analyses

2016-08-02 Thread Douglas N Greve
I have been doing simulations similar to #1 (Eklund) using surface-based analysis on both thickness and fMRI. I'll prepare a report of the results, but the early indications are that the same effect is in play, though it does not look like the effects are as bad as in Eklund. For thickness ana

[Freesurfer] Multiple Comparison Question for surface-based analyses

2016-08-01 Thread Ajay Kurani
Hello Freesurfer Experts, Recently there were two article published regarding clusterwise simulations for volumetric fmri analyses and potential errors for underestimating clusterwise extent thresholds. 1) http://www.pnas.org/content/113/28/7900.full.pdf?with-ds=yes 2) biorxiv.org/content/early