Re: [Freesurfer] Cortical thickness analysis on data acquired from multiple sites

2013-02-18 Thread Sinead Kelly
is. >> >> Chris >> __**__ >> From: >> freesurfer-boun...@nmr.mgh.**harvard.edu[ >> freesurfer-boun...@nmr.mgh.**harvard.edu] >> on behalf of Bruce Fischl [fis...@nmr.mgh.harvard.edu] >> Sent: Monday, February 18, 2013 1

Re: [Freesurfer] Cortical thickness analysis on data acquired from multiple sites

2013-02-18 Thread Bruce Fischl
.edu] on behalf of Bruce Fischl > [fis...@nmr.mgh.harvard.edu] > Sent: Monday, February 18, 2013 10:59 AM > To: Jorge Jovicich > Cc: Sinead Kelly; freesurfer@nmr.mgh.harvard.edu > Subject: Re: [Freesurfer] Cortical thickness analysis on data acquired from > multiple sites > > Hi

Re: [Freesurfer] Cortical thickness analysis on data acquired from multiple sites

2013-02-18 Thread Watson, Christopher
d.edu Subject: Re: [Freesurfer] Cortical thickness analysis on data acquired from multiple sites Hi Sinead I agree with Jorge - there is bound to be a substantial scanner effect. You might be better off keeping the data separate and treating the 3T as a confirmatory study. cheers Bruce On Mon, 18

Re: [Freesurfer] Cortical thickness analysis on data acquired from multiple sites

2013-02-18 Thread Bruce Fischl
Hi Sinead I agree with Jorge - there is bound to be a substantial scanner effect. You might be better off keeping the data separate and treating the 3T as a confirmatory study. cheers Bruce On Mon, 18 Feb 2013, Jorge Jovicich wrote: > Dear Sinead, > > we found global significant difference

Re: [Freesurfer] Cortical thickness analysis on data acquired from multiple sites

2013-02-18 Thread Jorge Jovicich
Dear Sinead, we found global significant differences in thickness between 1.5T and 3T, in a group of subjects that was scanned at both scanners (http://www.ncbi.nlm.nih.gov/pubmed/16651008). I think that nothing stops you from doing the analysis, but maybe model in a field effect to asset it i

[Freesurfer] Cortical thickness analysis on data acquired from multiple sites

2013-02-18 Thread Sinead Kelly
Dear members, I would like to get your opinion on this issue - I have a dataset of over 400 subjects but under half of this data was acquired on a 1.5T scanner and the rest was acquired on a 3T scanner. Would it be acceptable to conduct cortical thickness analysis on the combined dataset? From rea