Re: [Freesurfer] ICV/brain volume

2010-01-09 Thread Xiangchuan Chen
Hi Martin, I usually follow the "FreeSurfer Troubleshooting Reconstruction Work Flow" to do recon-all. So, I run "tkregister2 --mgz --s your_subject_name --fstal" to edit talairach transform. On ~/ fswiki/eTIV it is suggested to run " tkregister2 --xfm talairach.xfm --targ $FREESURFER_HOME/average

Re: [Freesurfer] ICV/brain volume

2010-01-09 Thread Martin Reuter
Hi Xiangchuan, In recent versions of Freesurfer, the atlas $FREESURFER_HOME/average/711-2C_as_mni_average_305.4dfp.img and the registration to that atlas found in $SUBJECTS_DIR/subjid/mri/transforms/talairach.xfm (created by talairach_avi, a script which calls imgreg_4dfp) is used to estimate ICV

Re: [Freesurfer] ICV/brain volume

2010-01-09 Thread Michael Harms
If you want to establish that the changes in a given region are in excess of any global atropy, then yes, I would agree that you want to use a measure of brain volume rather than ICV as a covariate. -MH > Hi Martin, Bruce and Mike, > > Thank you for all your suggestions. > > For Martin's suggest

Re: [Freesurfer] ICV/brain volume

2010-01-09 Thread Xiangchuan Chen
Hi Martin, Bruce and Mike, Thank you for all your suggestions. For Martin's suggestion: I found that it is hard to really fix the talairach transform for a lot of my subjects. In most cases, I tried to match the outlines between target and moveable images when running "tkregister2 --mgz --fstal -

Re: [Freesurfer] ICV/brain volume

2010-01-09 Thread Martin Reuter
Or you can fix the talairach transform and get the icv the standart way. When dividing by total brain vol, you undo atrophy. That's why icv is used. Martin On Jan 9, 2010, at 13:01, Bruce Fischl wrote: > or you could use mris_wm_volume, which excludes the interior of the > ventricles and g

Re: [Freesurfer] ICV/brain volume

2010-01-09 Thread Bruce Fischl
or you could use mris_wm_volume, which excludes the interior of the ventricles and gray matter structures, and mris_volume and the aseg to calculate it (adding the structures you are interested back in). Maybe we should start generating this # by default. Would enough people find it useful? ch

Re: [Freesurfer] ICV/brain volume

2010-01-09 Thread Michael Harms
You're correct that a small amount of hippocampus and amygdala falls outside the pial surface. However, it will be a TINY percentage of the whole brain volume, and MUCH smaller than variation of brain volume across individuals. So the little bit of hippocampus and amygdala that is "missed" will