I have the same bug with 8.10 (64 bits) on a Dell Inspiron 1501. When I
press Fn+Up to change the brightness, the keyboard stops to work and I
can't click on the gnome menu bar. I use Ctrl+Alt+F# as a workaround.
There was no such bug with Hardy.
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Losing keyboard and mouse control when changing
I don't know if it could be useful but the bug isn't triggered when
using Fn+Down..
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Losing keyboard and mouse control when changing screen brightness with fn +
arrow under intrepid
https://bugs.launchpad.net/bugs/285323
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Des