Re: [ccp4bb] His-His H-bond

2007-05-23 Thread Ian Ollmann
Histidine H-bond networks are sometimes used for facile proton migration between distal acid base pairs, especially in catalysis. You might look to see what is on the other side of each histidine. Ian

Re: [ccp4bb] L-alanosine

2007-07-05 Thread Ian Ollmann
You might check how these people did it: Huang J Lipscomb, Biochemistry, 2006 "T-state active site of aspartate transcarbamylase: crystal structure of the carbamyl phosphate and L-alanosine ligated enzyme." PubMedID: 16401065

Re: [ccp4bb] Kay Diederichs Email

2007-07-07 Thread Ian Ollmann
When an app crashes, you should be getting a little dialog box with the option to send a problem report of some kind to Apple. Send in the report. This sends in some diagnostic details about Mail.app state when the crash occurred to Apple. Like crash reports are grouped together in a databa

Re: [ccp4bb] Kay Diederichs Email

2007-07-07 Thread Ian Ollmann
On Jul 7, 2007, at 1:42 PM, Douglas L. Theobald wrote: S/MIME signed/encrypted messages started crashing my Mail app long ago, after one of the first updates to 10.4. I probably sent in a couple dozen of those crash reports, with absolutely zilch feedback, and of course I still have the pr

Re: [ccp4bb] Color of heme containing Xtals

2008-03-12 Thread Ian Ollmann
On Mar 12, 2008, at 12:48 PM, Jan Schoepe wrote: Hello everybody, I wonder if anybody has experience with heme (or to be more precise: heme b) containing proteins which Xtals do not look red under the microscope. How might the technique for crystallization (e.g. sitting drop, hanging drop

Re: [ccp4bb] ccp4 install on Leopard

2008-04-25 Thread Ian Ollmann
On Apr 25, 2008, at 3:14 PM, William Scott wrote: Yes, that is a general "problem" with sudo, with the latest version distributed in OS X. Briefly, sudo (and I have noticed other programs, like screen) don't inherit the environment, so sudo ccp4i no longer works. sudo -s spawns a root shell

Re: [ccp4bb] off-topic: Enzymology textbook recommendations?

2008-09-11 Thread Ian Ollmann
I'm not sure if kinetics is on the syllabus, but when I was doing enzyme kinetics work, this one was very important: http://www.amazon.com/Enzyme-Kinetics-Behavior-Equilibrium-Steady-State/dp/0471303097/ref=pd_bbs_sr_1?ie=UTF8&s=books&qid=1221171319&sr=8-1 On Sep 11, 2008, at 3:14 PM, Diana

Re: [ccp4bb] Crystallographic computing platform recommendations?

2008-11-18 Thread Ian Ollmann
On Nov 18, 2008, at 8:47 AM, Jeff Speir wrote: We also use OSX almost exclusively for our virus crystallography projects, for the same reasons given by Bill and Anastassis. Every now and then we have to spend time re-compiling some programs with larger parameters or up to 64-bit, so don't

Re: [ccp4bb] Crystallographic computing platform recommendations?

2008-11-18 Thread Ian Ollmann
On Nov 18, 2008, at 10:12 AM, Tim Fenn wrote: On Tue, 18 Nov 2008 10:21:29 + Kevin Cowtan <[EMAIL PROTECTED]> wrote: And I would give exactly the opposite advice, unless you are or have a guru who can devote time to fixing all the little things which still don't work under 64 bit OSs. (Do