Histidine H-bond networks are sometimes used for facile proton
migration between distal acid base pairs, especially in catalysis. You
might look to see what is on the other side of each histidine.
Ian
You might check how these people did it:
Huang J Lipscomb, Biochemistry, 2006 "T-state active site of
aspartate transcarbamylase: crystal structure of the carbamyl
phosphate and L-alanosine ligated enzyme."
PubMedID: 16401065
When an app crashes, you should be getting a little dialog box with
the option to send a problem report of some kind to Apple. Send in the
report. This sends in some diagnostic details about Mail.app state
when the crash occurred to Apple. Like crash reports are grouped
together in a databa
On Jul 7, 2007, at 1:42 PM, Douglas L. Theobald wrote:
S/MIME signed/encrypted messages started crashing my Mail app long
ago, after one of the first updates to 10.4. I probably sent in a
couple dozen of those crash reports, with absolutely zilch feedback,
and of course I still have the pr
On Mar 12, 2008, at 12:48 PM, Jan Schoepe wrote:
Hello everybody,
I wonder if anybody has experience with heme (or to be more precise:
heme b) containing proteins which Xtals do not look red under the
microscope. How might the technique for crystallization (e.g.
sitting drop, hanging drop
On Apr 25, 2008, at 3:14 PM, William Scott wrote:
Yes, that is a general "problem" with sudo, with the latest version
distributed in OS X.
Briefly, sudo (and I have noticed other programs, like screen) don't
inherit the environment, so
sudo ccp4i
no longer works.
sudo -s
spawns a root shell
I'm not sure if kinetics is on the syllabus, but when I was doing
enzyme kinetics work, this one was very important:
http://www.amazon.com/Enzyme-Kinetics-Behavior-Equilibrium-Steady-State/dp/0471303097/ref=pd_bbs_sr_1?ie=UTF8&s=books&qid=1221171319&sr=8-1
On Sep 11, 2008, at 3:14 PM, Diana
On Nov 18, 2008, at 8:47 AM, Jeff Speir wrote:
We also use OSX almost exclusively for our virus crystallography
projects, for the same reasons given by Bill and Anastassis. Every
now and then we have to spend time re-compiling some programs with
larger parameters or up to 64-bit, so don't
On Nov 18, 2008, at 10:12 AM, Tim Fenn wrote:
On Tue, 18 Nov 2008 10:21:29 + Kevin Cowtan
<[EMAIL PROTECTED]> wrote:
And I would give exactly the opposite advice, unless you are or have
a guru who can devote time to fixing all the little things which
still don't work under 64 bit OSs.
(Do