Re: [ccp4bb] Trying to "digest" PISA results

2011-09-05 Thread Huang, Jing
Jacob, You may also try DARTS (drug affinity responsive target stability). In this method, small molecule (or protein) binding leads to specific protection of its target protein from protease digestion. It is completely label free, and appears to be able to detect very low affinity interactions

Re: [ccp4bb] Trying to "digest" PISA results

2011-09-05 Thread Huang, Jing
& Medical Pharmacology 310-825-4329 jinghuang at mednet dot ucla dot edu http://labs.pharmacology.ucla.edu/huanglab/ From: Jacob Keller [j-kell...@fsm.northwestern.edu] Sent: Monday, September 05, 2011 12:18 PM To: Huang, Jing Cc: CCP4BB@JISCMAIL.AC.

Re: [ccp4bb] Trying to "digest" PISA results

2011-09-05 Thread Huang, Jing
ical Pharmacology 310-825-4329 jinghuang at mednet dot ucla dot edu http://labs.pharmacology.ucla.edu/huanglab/ From: Jacob Keller [j-kell...@fsm.northwestern.edu] Sent: Monday, September 05, 2011 3:44 PM To: Huang, Jing Cc: CCP4BB@JISCMAIL.AC.UK Subject: Re: [cc