Dear Amit,
I don’t think that PROCHECK is the right tool for assessing the quality of a
comparative model. It was revolutionary in its time, but the criteria it looks
at can mostly be satisfied by energy minimisation even of an incorrect model,
especially if you don’t have to simultaneously sa
Hi, All,
I am new to MicroED (microcrystal electron diffraction). I know that X-ray
crystallography has phase problem, and I think MicroED has phase problem
too (it is diffraction of electron instead of x-ray). However, when I read
the Wikipedia, I could not understand the following description of
Hi Alex,
Welcome to the field of microED! From a practical standpoint, microED also
suffers from the phase problem, and somewhat moreso compared to X-ray
crystallography because anomalous signal is very limited. It is true that a
TEM microscope operated in imaging mode produces images that contain
Dear colleagues,
We are currently looking to purchase a cell disruptor/homogeniser mainly for
routinely processing a few 100 mls of E. coli suspensions. With the current
COVID-19 restrictions it is very difficult for us to test any equipment. I thus
hope that some of you can share their experie
Dear Bernhard ,
I would recommend the emulsified from Avestin. It is great . Depending on
your budget you can ask for stainless steel (probe to slow tear ) or
ceramic (longer lasting but a bit more expensive).
We have the ceramic but I have worked with the stainless steel one and it
is really goo
