Hi,
Not sure what you mean by 'other way around' - the formula you drew is
what I was thinking about :) Mesomeric states in normal amidines are
averaged and should result in planarity - since this case does not seem to
have a planar geometry, there's a chance that the amidine never formed and
the
Dear Colleagues,
The amidine originating from the condensation reaction between the
Met N-formyl group and the His side chain should be the other way
around! This would also be roughly consistent with the reported
geometry. In fact, there should be two mesomeric states, provided
there is N pr
