Norman,
the value of free-R alone doesn't tell a whole lot, though the numbers you
quote seem good given the resolution. What's Rwork?
The behavior of free-R you tell is also totally expected: in rigid-body
refinement there are way less refinable parameters!
Most likely you should proceed with ind
hello everyone
I just noticed my model would give two very different Rfree
values from refmac depending which mode I use to refine it. Rigid
body it gives a Rfree value of 24.57% while restrained refinement
gives a value of 27.96%. Both are processed at 3.1angstrom
resolution. I am conf
