Re: [ccp4bb] off topic: Membrane protein "into" soluble protein

2019-03-06 Thread Bonsor, Daniel
[mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Andrew Lovering Sent: Wednesday, March 06, 2019 9:28 AM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] off topic: Membrane protein "into" soluble protein Dear ccp4bb members, A quick off topic question. I have a protein whose domain structure

[ccp4bb] off topic: Membrane protein "into" soluble protein

2019-03-06 Thread Andrew Lovering
Dear ccp4bb members, A quick off topic question. I have a protein whose domain structure runs N-TM-receptor-TM-enzyme-C, i.e. is a two transmembrane-helix containing signalling protein. One would suspect that the receptor domain has ends that cluster, and that the enzyme (via homology with know