Re: [ccp4bb] measuring shape complementarity

2010-12-06 Thread Mike Lawrence
Dear Mohd, CCP4 contains a program SC which does the job. sincerely Mike Lawrence, PhD Associate Professor and WEHI Fellow Division of Structural Biology Walter and Eliza Hall Institute of Medical Research 1G Royal Parade, Parkville Victoria 3052, AUSTRALIA Tel. 61-3-9345-2693 Fax 61-3-9345-

[ccp4bb] measuring shape complementarity

2010-12-06 Thread Salameh, Mohd A., Ph.D.
Dear All, I'm looking for a free program that I can use to measure the geometric surface complementarity of protein-protein interfaces. I have created inhibitor mutants that possess different binding affinities to their cognate enzyme and it would be very helpful if I can quantify the shape complem