Re: [ccp4bb] The input of CCP4-DM

2010-09-15 Thread Kevin Cowtan
zhan...@umbc.edu wrote: Hi Kevin: Thanks! Could you explain why the DM (NCS concerned) input should be Fo/PHIC/WCMB instead of FWT/PHIC? I thought DM is just a real-space phase improvement method, and the latter (FWT/PHIC) suffers less from model bias... No, DM does phase combination in recipr

Re: [ccp4bb] The input of CCP4-DM

2010-09-15 Thread Hailiang Zhang
Hi Kevin: Thanks! Could you explain why the DM (NCS concerned) input should be Fo/PHIC/WCMB instead of FWT/PHIC? I thought DM is just a real-space phase improvement method, and the latter (FWT/PHIC) suffers less from model bias... Best Regards, Hailiang > Hailiang Zhang wrote: >> If I have the

Re: [ccp4bb] The input of CCP4-DM

2010-09-15 Thread Kevin Cowtan
Hailiang Zhang wrote: If I have the model phase PHIC, exp Fo, and sigmaa-weighted FWT, is that more reasonable to use Fo/PHIC or FWT/PHIC as the input of CCP4-DM? You want Fo, sigFo, PHIC and the FOM from sigmaa or refmac. You might want to try parrot as well. If you feed it your MR model it

[ccp4bb] The input of CCP4-DM

2010-09-15 Thread Hailiang Zhang
Hi, If I have the model phase PHIC, exp Fo, and sigmaa-weighted FWT, is that more reasonable to use Fo/PHIC or FWT/PHIC as the input of CCP4-DM? Thanks! Best Regards, Hailiang