Dear Alisia
I assume you have read the documentation at
https://www.ccp4.ac.uk/html/scaleit.html
in particular the comment "Note that there is no unique solution to the problem
of scaling together two different data sets. “
The program was written (a long time ago) to scale a heavy-atom deriva
Hello, scaleit is for derivative-to-native scaling whereas the Fox and Holmes
method is generally for batch scaling and merging, as done, for example, by
scala and its successors, but it is all non-linear least squares, so the
methods will be fundamentally the same. Hope this helps a bit, Jon.C.
Dear all,
I am having trouble following from the documentation what specific functions
are minimized in SCALEIT for the different REFINE options and how the
Fox&Holmes method is applied. Any insight would be very helpful!
All the best,
Alisia
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