all, no concrete evidence for such).
Therefore, perhaps all designs by humans would also be mere illusions...ah!
but they seem so much like the product of an intelligence!
JPK
- Original Message -
From: "Ed Pozharski"
To:
Sent: Wednesday, September 08, 2010 8:29 PM
Subject:
A large amount of hypotheticals can be found in Plasmodium :-)
Jürgen
-
Jürgen Bosch
Johns Hopkins Bloomberg School of Public Health
Department of Biochemistry & Molecular Biology
Johns Hopkins Malaria Research Institute
615 North Wolfe Street, W8708
Baltimore, MD 21205
Phone: +1-410-614-4742
Lab:
David is absolutely right. There is no design, Jacob, we just
instinctively look for it everywhere because seeking purpose instead of
understanding mechanism conveys advantage to our species. Your
rationale is flawed - just because it is imaginable (with caveats) does
not mean that it must exist
rtain rare tRNAs (for Arg, Ile, Leu, and Pro in the cell line
> mentioned), thereby increasing their availability and subsequent usage.
>
> Keep chasing that Nobel Prize, but have a backup plan...you're clearly very
> creative.
>
> Mike
>
>
> ----- Original Mess
spite their commonness and high importance.
- Original Message -
From: "Artem Evdokimov"
To:
Sent: Tuesday, September 07, 2010 8:29 PM
Subject: Re: [ccp4bb] Reverse Translatase
Regardless of whether a system like this exists in Nature or not -
it's fun to imagine!
O
On 09/07/10 22:10, Jacob Keller wrote:
In terms of "usefulness," I was actually thinking about cells learning how
to make new proteins from other cells,
Which they do already by exchanging genes
or perhaps an immune system could use
the info to make the right choice of starting materials.
Th
I shell correct myself.
The Darwin evolution of species is not sufficient to perform all
functions of the reverse translatase. The Nature also uses viruses in
order to "translate" proteins from different species. The other forms
of reverse translation were probably not needed before the
in
Doesn't natural selection act like a Reverse Translatase? Which is
quite an elegant implementation of the idea...
On Sep 7, 2010, at 6:29 PM, Artem Evdokimov wrote:
Regardless of whether a system like this exists in Nature or not -
it's fun to imagine!
On a microscopic scale one could propos
- Original Message -
From: "Artem Evdokimov"
To:
Sent: Tuesday, September 07, 2010 8:29 PM
Subject: Re: [ccp4bb] Reverse Translatase
Regardless of whether a system like this exists in Nature or not -
it's fun to imagine!
On a microscopic scale one could propose a hypo
Regardless of whether a system like this exists in Nature or not -
it's fun to imagine!
On a microscopic scale one could propose a hypothetical mechanism by
which a completely unfolded polypeptide chain could be fed into a
gated (or state-locked) peptidase that may break the chain down in a
co-ord
On 09/06/10 21:36, Jacob Keller wrote:
Dear Crystallographers,
does anyone know of any conceptual reason why a reverse translatase enzyme
(protein-->nucleic acid) could not exist? I can think of so many things for
which such an enzyme would be helpful, both to cells and to scientists...!
Unless
48895
From: CCP4 bulletin board [ccp...@jiscmail.ac.uk] On Behalf Of Greg
Alushin [galus...@berkeley.edu]
Sent: Tuesday, September 07, 2010 3:19 AM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] Reverse Translatase
Hi Jacob-
What an intriguing proposition.
erkeley.edu]
Sent: Tuesday, September 07, 2010 3:19 AM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] Reverse Translatase
Hi Jacob-
What an intriguing proposition. I can think of multiple reasons why
such a system would not exist, but there is a mechanistic one which is
most fundamental, havi
ideas coming,
Mike Thompson
- Original Message -
From: "Jacob Keller"
To: CCP4BB@JISCMAIL.AC.UK
Sent: Monday, September 6, 2010 6:36:14 PM GMT -08:00 US/Canada
Pacific
Subject: [ccp4bb] Reverse Translatase
Dear Crystallographers,
does anyone know of any conceptual re
al Message -
From: "Jacob Keller"
To: CCP4BB@JISCMAIL.AC.UK
Sent: Monday, September 6, 2010 6:36:14 PM GMT -08:00 US/Canada Pacific
Subject: [ccp4bb] Reverse Translatase
Dear Crystallographers,
does anyone know of any conceptual reason why a reverse translatase enzyme
(protein-->
Dear Crystallographers,
does anyone know of any conceptual reason why a reverse translatase enzyme
(protein-->nucleic acid) could not exist? I can think of so many things for
which such an enzyme would be helpful, both to cells and to scientists...!
Unless there is something I am missing, it w
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