On Fri, Jul 12, 2013 at 1:08 AM, Stefan Krimmer <
krim...@staff.uni-marburg.de> wrote:
> in some of my macromolecular crystal structures with resolutions between
> 1.1 - 1.4 Å, several round positive Fo-Fc electron density blobs are
> detectable which show after assignment of a water molecule to t
You are desribing the reason many people limit their refinement to lower
resolution! I think it is probably universally true that there are multiple
conformations for sidechain/water networks at the surface, which we just
dont model properly. If you are going to tackle the fine details you need
to
Dear all,
I have a question concerning the refinement of partly occupied water
molecules:
in some of my macromolecular crystal structures with resolutions
between 1.1 - 1.4 Å, several round positive Fo-Fc electron density
blobs are detectable which show after assignment of a water molecul
