Re: [ccp4bb] Refinement: Basic questions

2009-02-13 Thread Tim Gruene
-BEGIN PGP SIGNED MESSAGE- Hash: SHA1 On Fri, 13 Feb 2009, Andy Millston wrote: I have some very basic questions about model refinement process. 1. Why Refmac5 refinement from Coot GUI gives different results than Refmac5 refinement from CCP4i? One obvious difference is that COOT ref

[ccp4bb] Refinement: Basic questions

2009-02-13 Thread Andy Millston
I have some very basic questions about model refinement process. 1. Why Refmac5 refinement from Coot GUI gives different results than Refmac5 refinement from CCP4i? One obvious difference is that COOT refinements are local whereas CCP4i refinements are global. But why should it make a major dif