On Thursday 04 March 2010 02:45:20 Miles Pufall wrote:
> Dear All -
>
> Does anyone have some good examples where a post-translational modification
> has induced local structure?
> I'm particularly thinking of structure induced by the modification only and
> not something
> multi-step like a
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发件人: CCP4 bulletin board [mailto:ccp...@jiscmail.ac.uk] 代表 Paul Mcewan
发送时间: 2010年3月4日 20:21
收件人: CCP4BB@JISCMAIL.AC.UK
主题: Re: [ccp4bb] Post-translational modification induced strcture
Title: Re: [ccp4bb] Post-translational modification induced strcture
Collagen probably isn't a great example as hydroxylation of proline in collagen enhances the thermal stability of collagen, it doesn't really "induce" collagen structure, as unhydroxylated (pro-pro
Hi Miles -
I would say a good example of that phenomenon is collagen, where
hydroxylation of the prolyl residues alows the polypeptide to adopt
its helical conformation. In that case it is the fact there is an
electronegative substituent on the prolyl ring that biases it into a
particular conforma
Dear All -
Does anyone have some good examples where a post-translational modification has
induced local structure? I'm particularly thinking of structure induced by the
modification only and not something multi-step like a modification that
recruits a cofactor that induces structure.
Than
