Re: [ccp4bb] Pisa application

On 08/08/2012 09:00 AM, Jose Duarte wrote: To my knowledge PISA by itself is not able to do interface prediction To my understanding PISA is not *intended* to do interface prediction

Re: [ccp4bb] Pisa application

Hi Careina, I asked the exactly same question in this year's CCP4 summer school @APS, and the answer I got was "no ... PISA is not for predicting...". Cheers, Xun Sent from my iPad On Aug 8, 2012, at 2:33 AM, Careina Edgooms wrote: > Dear ccp4ers > > I just wonder whether anybody

Re: [ccp4bb] Pisa application

Perhaps IBIS does what you want? http://www.ncbi.nlm.nih.gov/Structure/ibis/ibis.cgi "IBIS ... infers/predicts interacting partners and binding sites by homology " -- David On 8 August 2012 07:33, Careina Edgooms wrote: > Dear ccp4ers > > I just wonder whether anybody knows if the PISA softwa

Re: [ccp4bb] Pisa application

Hi Careina To my knowledge PISA by itself is not able to do interface prediction. In any case there are a few methods available for protein-protein interface prediction. See for example this nice compilation: http://rosettadesigngroup.com/blog/58/10-protein-protein-interface-prediction-server

Re: [ccp4bb] Pisa application

Maybe Nat Protoc. 2011 Aug 11;6(9):1341-54. doi: 10.1038/nprot.2011.367. Predic

[ccp4bb] Pisa application

Dear ccp4ers I just wonder whether anybody knows if the PISA software could be used/modified to detect potential interfaces of interaction of different proteins? This would be very useful as a tool to validate protein-protein interactions detected by in vivo methods such as yeast 2 hybrid scree