Re: [ccp4bb] Mg++ interactions

2012-12-02 Thread Malcolm Walkinshaw
SENT ON BEHALF OF DR MARJORIE HARDING I would not rule out Mg++ ever coordinating with a primary amine, but it is much rarer than the reports in Mespeus suggest. Mg++ with arginine: Mespeus 10 finds 36 examples, but quick inspection of the list shows that almost all have coordination number

Re: [ccp4bb] Mg++ interactions

2012-11-30 Thread Ed Pozharski
On Tue, 2012-11-27 at 21:46 -0800, William G. Scott wrote: > Are Mg++ ions ever observed to chelate primary amines? MESPEUS reports, for example, 13 structure where magnesium is coordinated by a lysine. 7 with arginines and a bunch of asn/gln side chains as well. It does not prove, of course, th

[ccp4bb] Mg++ interactions

2012-11-29 Thread Carter, Charlie
Begin forwarded message: Date: November 28, 2012 8:18:37 AM EST To: "William G. Scott" mailto:wgsc...@ucsc.edu>> Subject: Re: [ccp4bb] Mg++ interactions Bill, I cannot answer your question, except to comment that in many, if not all Class I aminoacyl-tRNA synthetases, Mg

[ccp4bb] Mg++ interactions

2012-11-27 Thread William G. Scott
Hi folks: Are Mg++ ions ever observed to chelate primary amines? Are there any examples in crystal structures? Thanks. -- Bill William G. Scott Professor Department of Chemistry and Biochemistry and The Center for the Molecular Biology of RNA 228 Sinsheimer Laboratories University of Calif