Rwork = 0.26 and Rfree = 0.32 are not necessarily unacceptably high
for a 2.3 A dataset in my opinion.
Not all crystals are the same, some just have more disorder than
others and not all of this disorder is modelable (if that is a word).
Having said that:
- is the 2.3A data cutoff perhaps a ta
Hello-
I am working up a data that is giving me unacceptable high R factors.
I am solving a data set that is good to ~ 2.3 Å using molecular
replacement based on a previously crystalized variant. The maps look
good with all the density fitting well to my model. I originally
worked up the