Re: [ccp4bb] High R factors in Orthorhombic Space Group

2009-12-03 Thread mjvanraaij
Rwork = 0.26 and Rfree = 0.32 are not necessarily unacceptably high for a 2.3 A dataset in my opinion. Not all crystals are the same, some just have more disorder than others and not all of this disorder is modelable (if that is a word). Having said that: - is the 2.3A data cutoff perhaps a ta

[ccp4bb] High R factors in Orthorhombic Space Group

2009-12-03 Thread Robert Radford
Hello- I am working up a data that is giving me unacceptable high R factors. I am solving a data set that is good to ~ 2.3 Å using molecular replacement based on a previously crystalized variant. The maps look good with all the density fitting well to my model. I originally worked up the