This paper might provide some inspiration!
Crystallization of protein–ligand complexes
A Hassell et al
Acta Crystallogr D Biol Crystallogr
2006 vol. 63 (1) pp. 72-79
HTH,
Dave
David C. Briggs PhD
University of Manchester E-mail:
david.c.b
Dear all,
I am trying to get enzyme-ligand complexes crystals. I have already tried
co-crystallization and soaking, but it was just failed. Are there some new
methods developed for geting enzyme-ligand complexes crystals, or new
strategies for co-crystallization and soaking recently? Thanks