I think that two issues are being confused here. When the anomalous signal
is very weak, e.g. for sulfur-SAD phasing, the anomalous differences are
comparable with the intensity esds. By averaging over many measurements we
can reduce these esds and so improve the signal to noise ratio and the
ch
[switch not too serious mode on]:
well, it is lysozyme, which, according to diffraction properties, should
perhaps be classified as a salt (LyCl7), not a protein... :-)
Mark J van Raaij
Laboratorio M-4
Dpto de Estructura de Macromoleculas
Centro Nacional de Biotecnologia - CSIC
c/Darwin 3, Campu
Dear all,
We have solved the sturcture of hen egg white lysozyme
with a barium ion at 2.7 fold data redundancy. Data collected at in-house
copper K-alpha source to 2.22 A resolution with 1 degree oscillation step
per frame. The substructure was correctly identified with just 8
