Re: [ccp4bb] All-D World

2012-02-16 Thread Frank von Delft
I believe Eric is paraphrasing Genesis 3. It's all the serpent's fault. http://www.ic.unicamp.br/~stolfi/PUB/misc-misc/GenesysParody.html On 16/02/2012 02:39, Eric Bennett wrote: Jacob, I wish it were that cheery. Do

Re: [ccp4bb] All-D World

2012-02-15 Thread Eric Bennett
Jacob, I wish it were that cheery. Do not forget the darker side of history. The prefix "L-" stands for levorotary. The "levo" comes from the Latin wording for "left side". Left handedness is also known as sinistrality, from the Latin "sinistra" which also meant the left side, but over time

Re: [ccp4bb] All-D World

2012-02-15 Thread Jacob Keller
G-d is right-handed, so to speak: Ex 15:6 "Thy right hand, O LORD, is become glorious in power: thy right hand, O LORD, hath dashed in pieces the enemy." Since we are made in His image, and our (chiral) molecules are the cause of making most of us right-handed, which enantiomer to use was not a r

Re: [ccp4bb] All-D World

2012-02-15 Thread Katherine Sippel
Well if you think about it technically God produced plants within three days which if far too little work for a thesis. Maybe it could count as preliminary results for one aim of a thesis proposal so it might be enough to get PhD candidacy depending on how demanding your committee is. You could alw

Re: [ccp4bb] All-D World

2012-02-15 Thread William G. Scott
Hi Jacob: After giving this a great deal of reflection ….. I realized that you would face the same paradox that God had to resolve six thousand years ago at the Dawn of Creation, i.e., He needed D-deoxyribose DNA to code for L-amino acid proteins, and vice versa. Likewise, you would probably be f

[ccp4bb] ccp4bb] All-D World

2012-02-15 Thread Miri Hirshberg
Weds., Feb. 15th 2012 EBI Good evening, PDB entries with spg P 1- or I -4 C 2 are 3al1 3boi 2gpm 1krl 2gq7 2gq6 2gq5 2gq4 2g32 1pup 3e7r 1vtu 3odv 3trw 3try you can get information on each from pdbe pdbe.org/entry i.e. pdbe.org/3al1 etc. Miri, PDBe On Wed, 15 Feb 2012, Jacob Keller wrote:

Re: [ccp4bb] All-D World

2012-02-15 Thread Ho,Shing
The structure of an all D-amino acid version of the HIV-1 protease was solved in 1992 (see Milton, Milton, and Kent, 1992, Science, 256:1445-1448). The D-enzyme was seen to have a structure that is the mirror image of the L-enzyme, and showed specificity for the enantiomeric form of the chiral subs

[ccp4bb] All-D World

2012-02-15 Thread Jacob Keller
So who out there wants to start an all-D microbial culture by total synthesis, a la the bacterium with the synthetic genome a while back? Could it work, I wonder? I guess that would be a certain benchmark for Man's conquest of nature. JPK ps maybe if there is a broadly-acting amino-acid isomerase