Re: [ccp4bb] AW: [ccp4bb] modified amino acids in the PDB

2013-07-09 Thread Engin Özkan
Unfortunately, not all is ever that easy. If we were to follow Mark's rules, glycoproteins would end up losing their asparagines (and others residues depending on the type of glycosylation) to numerous underdefined new residue types. And consider the confusion caused by the different versions o

[ccp4bb] AW: [ccp4bb] modified amino acids in the PDB

2013-07-09 Thread Herman . Schreuder
Dear Marc (and BB), I guess as usual, in real life the obvious is less obvious as it seems to be. I, and I guess many of my colleagues trying to find new drugs, have quite a few protein-inhibitor complexes where the inhibitor formed a covalent link with e.g. the active site serine. In these cas